The American Academy of Pediatric Dentistry recognizes the emerging field of regenerative medicine and encourages dentists to follow evidence-based literature in order to educate parents about the collection, storage, viability, and use of dental stem cells with respect to autologous regenerative therapies. The American Academy of Pediatric Dentistry also recognizes that harvested dental stem cells is an emerging science which may have application for oral health care but at present there are no treatments available using harvested dental stem cells in humans. This policy is related to the use of harvested dental stem cells from a tooth or follicle. This policy does not include stem cells which are intrinsically present for treatment related to regenerative endodontics from the apical papilla or dental pulp cells. Stem cells used for regenerative endodontics and scaffolding have evidenced-based literature to show successful regeneration.1-3